Sarudza Isu
JDK ndiyo ine yekutanga-kirasi yekugadzira zvivakwa uye Hunhu manejimendi emidziyo, iyo inovimbisa kugadzikana kupihwa kweAPI yepakati.Chikwata chehunyanzvi chinovimbisa R&D yechigadzirwa.Kupesana nezvose, tiri kutsvaga CMO & CDMO mumusika wepamba uye wepasirese.
Product Description
Pakati payo, 17-amino-10-oxy-3,6,12,15-tetraoxa-9-azaheptadecanoic acid isanganiswa yakaoma ine simba guru mune zvakasiyana-siyana zvekushandisa.Chimiro chayo chemorekuru uye yakasarudzika musanganiswa wezvinhu zvinoita kuti ive chinhu chakakosha pakuvandudza zvinodhaka, biochemistry uye zvine chekuita nesainzi kuedza.
Chimwe chezvinhu zvikuru zvechigadzirwa ichi ndechekusiyana-siyana kwayo.17-Amino-10-oxy-3,6,12,15-tetraoxa-9-azaheptadecanoic acid inogona kushandiswa sechivakwa chekuvaka mukugadzirwa kwemhando dzakasiyana-siyana dzebioactive molecules, dzakadai se peptides uye mapuroteni.Mapoka ayo anoshanda uye amino acid sequences anogonesa kunyatsoita uye kwakanyatso kuchinjika, kuve nechokwadi chepamusoro chekutonga uye chakanangana nekugadzirwa kwezvinodhaka.
Vatsvaguri nemasaenzi muminda yekurapa uye kuwanikwa kwezvinodhaka vanobatsirikana zvakanyanya nekubatanidza chigadzirwa ichi mukutsvaga kwavo.Zvingango shandiswa zvinotangira kubva kune zvakanangwa zvirongwa zvekuunza zvinodhaka kusvika pakuvandudzwa kweanova erapeutic agents.Nekushandisa iyo yakasarudzika zvivakwa zve17-amino-10-oxy-3,6,12,15-tetraoxa-9-azaheptadecanoic acid, makambani emishonga anogona kuvandudza nekugadzira kurapa kwezvirwere zvakasiyana siyana.
Mukuwedzera, kusimba kwechigadzirwa kunovimbisa kugadzikana uye kuvimbika pasi pemamiriro akasiyana-siyana ekuedza.Huremu hwayo hwemamorekuru uye kuumbwa kwacho kwakanyatso kugadzirwa kuti ipe optimal solubility, zvichibvumira kubatanidzwa kuri nyore mumaprotocol ekuedzwa.Pamusoro pezvo, kuchena kwechigadzirwa uye kuenderana kunovimbisa kudzokororwa mhedzisiro, zvichiita kuti ive chishandiso chakakosha chemhedzisiro yekutsvagisa yakavimbika.
Kana zvasvika pakuchengetedzeka, tinotora chenjedzo dzese kuti tive nechokwadi chekuti 17-amino-10-oxy-3,6,12,15-tetraoxa-9-azaheptadecanoic acid inosangana nemhando yepamusoro-soro.Matanho akasimba ekudzora emhando inotorwa mukati mekugadzira maitiro kuti ave nechokwadi chekushaikwa kwehupi hupi husina tsvina kana kusvibiswa.
![Tofacitinib Intermediate (2R, 3R) -2,3-bis [(4-methylbenzoyl) oxy] succinic acid uye (3R, 4R) - N, 4-dimethyl-1- (phenylmethyl) -3-piperidine amine CAS No. 477600 -71-8](http://cdn.globalso.com/jdkhc/2R-3R-23-bis-4-methylbenzoyl-oxy-succinic-acid-and-3R-4R-N-4-dimethyl-1-phenylmethyl-3-piperidine-amine.jpg)
