Tsanangudzo
Topirastat yepakati 2-cyanoisonicotinic acid, CAS Nhamba 161233-97-2.Ichi chigadzirwa chinozivikanwawo nemamwe mazita: 2-cyanopyridine-4-carboxylic acid, 2-cyano-4-pyridinecarboxylic acid, uye 4-pyridinecarboxylic acid, 2-cyano-.Iyo molecular formula yeiyi yepakati kompani ndeye C7H4N2O2 uye huremu hwemamorekuru ndeye 148.1189.Icho chikamu chakakosha mukugadzirwa kwe topirastat (chirwere chinoshandiswa kurapa hyperuricemia mune gout varwere).
2-Cyanoisonicotinic acid inoita basa rakakosha mukugadzirwa kwe topirastat, inoshanda nekudzivisa xanthine oxidase, enzyme inobatanidzwa mukugadzirwa kweuric acid.Nekuda kweizvozvo, mazinga euric acid muropa anodzikira, achibvisa zviratidzo zvevarwere vegout.Ichi chikamu chepakati chinhu chakakosha mukugadzirwa kwe topirastat, zvichiita kuti ive chikamu chakakosha cheindasitiri yemishonga.
Sarudza Isu
JDK ndiyo ine yekutanga-kirasi yekugadzira zvivakwa uye Hunhu manejimendi emidziyo, iyo inovimbisa kugadzikana kupihwa kweAPI yepakati.Chikwata chehunyanzvi chinovimbisa R&D yechigadzirwa.Kupesana nezvose, tiri kutsvaga CMO & CDMO mumusika wepamba uye wepasirese.
![Tofacitinib Intermediate (2R, 3R) -2,3-bis [(4-methylbenzoyl) oxy] succinic acid uye (3R, 4R) - N, 4-dimethyl-1- (phenylmethyl) -3-piperidine amine CAS No. 477600 -71-8](http://cdn.globalso.com/jdkhc/2R-3R-23-bis-4-methylbenzoyl-oxy-succinic-acid-and-3R-4R-N-4-dimethyl-1-phenylmethyl-3-piperidine-amine.jpg)
